abstract：BACKGROUND:Most studies on the human microbiota have analyzed stool samples, although a large proportion of the absorption of nutrients takes place in upper gut tract. We collected samples from different locations along the entire gastrointestinal tract from six patients who had simultaneously undergone upper endoscopy...

journal_title：BMC microbiology

authors： Mailhe M,Ricaboni D,Vitton V,Gonzalez JM,Bachar D,Dubourg G,Cadoret F,Robert C,Delerce J,Levasseur A,Fournier PE,Angelakis E,Lagier JC,Raoult D

更新日期：2018-10-24 00:00:00

abstract：BACKGROUND:Campylobacter jejuni (C. jejuni) is a leading cause of foodborne gastroenteritis worldwide. This bacterium lacks many of the classical virulence factors, and flagellum-associated persistent colonization has been shown to be crucial for its pathogenesis. The flagellum plays a multifunctional role in C. jejuni...

journal_title：BMC microbiology

authors： Ren F,Li X,Tang H,Jiang Q,Yun X,Fang L,Huang P,Tang Y,Li Q,Huang J,Jiao XA

更新日期：2018-10-22 00:00:00

abstract：BACKGROUND:Aspergillus fumigatus is a ubiquitous saprotrophic fungus and an opportunistic pathogen of humans and animals. Humans and animals can inhale hundreds of A. fumigatus spores daily. Normally this is harmless for humans, but in case of immunodeficiency, invasive pulmonary aspergillosis (IPA) can develop with a ...

journal_title：BMC microbiology

authors： Valdes ID,van den Berg J,Haagsman A,Escobar N,Meis JF,Hagen F,Haas PJ,Houbraken J,Wösten HAB,de Cock H

更新日期：2018-09-17 00:00:00

abstract：BACKGROUND:The Gram-negative phytopathogenic bacterium Xanthomonas campestris pv. campestris recruits the hrp/T3SS system to inject pathogenicity effector proteins into host cells and uses the rpf/DSF cell-cell signaling system to regulate the expression of virulence factors such as extracellular enzymes and polysaccha...

journal_title：BMC microbiology

authors： Jiang BL,Jiang GF,Liu W,Yang LC,Yang LY,Wang L,Hang XH,Tang JL

更新日期：2018-09-03 00:00:00

abstract：BACKGROUND:Anthrax, the zoonotic disease caused by the gram-positive bacterium Bacillus anthracis, is nowadays rare in northern parts of Europe including Finland and Scandinavia. Only two minor outbreaks of anthrax in 1988 and in 2004 and one sporadic infection in 2008 have been detected in animals in Finland since the...

journal_title：BMC microbiology

authors： Lienemann T,Beyer W,Pelkola K,Rossow H,Rehn A,Antwerpen M,Grass G

更新日期：2018-09-03 00:00:00

abstract：BACKGROUND:Non typhoidal salmonellosis is one of the neglected zoonoses in most African countries. The use of sub-therapeutic doses of antibiotics as animal growth promoter enhances the emergence and dissemination of antimicrobial resistance in bacteria with food animal reservoirs and may also results in antibiotics re...

journal_title：BMC microbiology

authors： Adetoye A,Pinloche E,Adeniyi BA,Ayeni FA

更新日期：2018-08-30 00:00:00

abstract：BACKGROUND:The naked mole-rat (NMR, Heterocephalus glaber) is being bred as a novel laboratory animal due to its unique biological characteristics, including longevity, cancer resistance, hypoxia tolerance, and pain insensitivity. It is expected that differences exist between the microbiota of wild NMRs and that of NMR...

journal_title：BMC microbiology

authors： Cong W,Xing J,Feng Y,Wang J,Fu R,Yue B,He Z,Lin L,Yang W,Cheng J,Sun W,Cui S

更新日期：2018-08-22 00:00:00

abstract：BACKGROUND:Legionella pneumophila, the causative agent of Legionnaire's disease, may enter a viable but non-culturable (VBNC) state triggered by environmental stress conditions. Specific outer-membrane epitopes of L. pneumophila are used in many diagnostic applications and some of them are linked to important virulence...

journal_title：BMC microbiology

authors： Schrammel B,Petzold M,Cervero-Aragó S,Sommer R,Lück C,Kirschner A

更新日期：2018-07-17 00:00:00

abstract：BACKGROUND:Bovine tuberculosis (bTB) caused by Mycobacterium bovis is the most serious endemic disease affecting livestock in the UK. The European badger (Meles meles) is the most important wildlife reservoir of bTB transmission to cattle, making eradication particularly difficult. In this respect, oral vaccination wit...

journal_title：BMC microbiology

authors： Stedman A,Maluquer de Motes C,Lesellier S,Dalley D,Chambers M,Gutierrez-Merino J

更新日期：2018-07-13 00:00:00

abstract：BACKGROUND:The development of vaccines and evaluation of novel treatment strategies for invasive group A streptococcal (iGAS) disease requires suitable models of human infection that can be monitored longitudinally and are preferably non-invasive. Bio-photonic imaging provides an opportunity to reduce use of animals in...

journal_title：BMC microbiology

authors： Lamb LE,Zhi X,Alam F,Pyzio M,Scudamore CL,Wiles S,Sriskandan S

更新日期：2018-06-19 00:00:00

abstract：BACKGROUND:Iron plays important roles in the growth, reproduction and pathogenicity of Aeromonas hydrophila. In this study, we detected and compared the mRNA and protein expression profiles of A. hydrophila under normal and iron restricted medium with 200 μM 2,2-Dipyridyl using RNA Sequencing (RNA-seq) and isobaric tag...

journal_title：BMC microbiology

authors： Teng T,Xi B,Chen K,Pan L,Xie J,Xu P

更新日期：2018-06-04 00:00:00

abstract：BACKGROUND:Identification and characterization of non-typeable Haemophilus influenzae (NTHi) with reduced susceptibility to β-lactam antibiotics due to mutations in penicillin binding protein 3 (PBP3) is a clinical challenge. We analyzed a blood isolate, NTHi93-57485, that was categorized as aminopenicillin resistant b...

journal_title：BMC microbiology

authors： Thegerström J,Matuschek E,Su YC,Riesbeck K,Resman F

更新日期：2018-05-31 00:00:00

abstract：BACKGROUND:Alleviating arsenic (As) contamination is a high-priority environmental issue. Hyperaccumulator plants may harbor endophytic bacteria able to detoxify As. Therefore, we investigated the distribution, diversity, As (III) resistance levels, and resistance-related functional genes of arsenite-resistant bacteria...

journal_title：BMC microbiology

authors： Gu Y,Wang Y,Sun Y,Zhao K,Xiang Q,Yu X,Zhang X,Chen Q

更新日期：2018-05-08 00:00:00

abstract：BACKGROUND:Global warming has triggered an increase in the prevalence and severity of coral disease, yet little is known about coral/pathogen interactions in the early stages of infection. The point of entry of the pathogen and the route that they take once inside the polyp is currently unknown, as is the coral's capac...

journal_title：BMC microbiology

authors： Gibbin E,Gavish A,Domart-Coulon I,Kramarsky-Winter E,Shapiro O,Meibom A,Vardi A

更新日期：2018-04-20 00:00:00

abstract：ERRATUM:Upon publication of the original article (1) it was highlighted by the authors that a grant awarded to support the research work of the study was missed in the acknowledgements. It should also be acknowledged that the grant titled "Genotyping and Molecular Epidemiological Characteristic of Bacillus anthracis in...

journal_title：BMC microbiology

authors： Li S,Ma Q,Chen H,Wang D,Liu Y,Wei X,You L,Yao G,Tian K,Tang G

更新日期：2018-04-12 00:00:00

abstract：BACKGROUND:We and others have previously shown that alterations in the mammalian gut microbiome are associated with diet, notably early life exposure to a maternal high fat diet (HFD). Here, we aimed to further these studies by examining alterations in the gut microbiome of juvenile Japanese macaques (Macaca fuscata) t...

journal_title：BMC microbiology

authors： Pace RM,Prince AL,Ma J,Belfort BDW,Harvey AS,Hu M,Baquero K,Blundell P,Takahashi D,Dean T,Kievit P,Sullivan EL,Friedman JE,Grove K,Aagaard KM

更新日期：2018-04-05 00:00:00

abstract：BACKGROUND:The aim of this study was to identify mutations of rpoB, katG, inhA and ahp-genes associated Mycobacterium tuberculosis resistance to rifampicin (RIF) and isoniazid (INH) in Kyrgyz Republic. We studied 633 smear samples from the primary pulmonary tuberculosis (TB) patients. We verified Mycobacterium tubercul...

journal_title：BMC microbiology

authors： Isakova J,Sovkhozova N,Vinnikov D,Goncharova Z,Talaibekova E,Aldasheva N,Aldashev A

更新日期：2018-03-22 00:00:00

abstract：BACKGROUND:Recurrent acute otitis media (rAOM, recurrent ear infection) is a common childhood disease caused by bacteria termed otopathogens, for which current treatments have limited effectiveness. Generic probiotic therapies have shown promise, but seem to lack specificity. We hypothesised that healthy children with ...

journal_title：BMC microbiology

authors： Lappan R,Imbrogno K,Sikazwe C,Anderson D,Mok D,Coates H,Vijayasekaran S,Bumbak P,Blyth CC,Jamieson SE,Peacock CS

更新日期：2018-02-20 00:00:00

abstract：BACKGROUND:Brucellosis incidence in China is divided into three stages: high incidence (1950s-1960s), decline (1970s-1980s), and re-emergence (1990s-2010s). At the re-emergence stage, Brucellosis incidence grew exponentially and spread to all 32 provinces. We describe the magnitude and the etiological distribution chan...

journal_title：BMC microbiology

authors： Piao DR,Liu X,Di DD,Xiao P,Zhao ZZ,Xu LQ,Tian GZ,Zhao HY,Fan WX,Cui BY,Jiang H

更新日期：2018-01-10 00:00:00

abstract：BACKGROUND:Hypervirulent K. pneumoniae (hvKp) causes severe community acquired infections, predominantly in Asia. Though initially isolated from liver abscesses, they are now prevalent among invasive infections such as bacteraemia. There have been no studies reported till date on the prevalence and characterisation of ...

journal_title：BMC microbiology

authors： Shankar C,Veeraraghavan B,Nabarro LEB,Ravi R,Ragupathi NKD,Rupali P

更新日期：2018-01-08 00:00:00

abstract：BACKGROUND:Demand for high-throughput bioprocessing has dramatically increased especially in the biopharmaceutical industry because the technologies are of vital importance to process optimization and media development. This can be efficiently boosted by using microtiter plate (MTP) cultivation setup embedded into an a...

journal_title：BMC microbiology

authors： Tan JS,Abbasiliasi S,Kadkhodaei S,Tam YJ,Tang TK,Lee YY,Ariff AB

更新日期：2018-01-04 00:00:00

abstract：BACKGROUND:Bacillus spp. have prominent ability to suppress plant pathogens and corresponding diseases. Previous analyses of Bacillus spp. revealed numerous gene clusters involved in nonribosomal synthesis of cyclic lipopeptides with distinct antimicrobial action. The 4'-phosphopantetheinyl transferase (PPTase) encoded...

journal_title：BMC microbiology

authors： Jin P,Wang H,Liu W,Miao W

更新日期：2017-12-04 00:00:00

abstract：BACKGROUND:Persister cells comprise a phenotypic variant that shows extreme antibiotic tolerance resulting in treatment failures of bacterial infections. While this phenomenon has posed a great threat in public health, mechanisms underlying their formation in Staphylococcus aureus remain largely unknown. Increasing evi...

journal_title：BMC microbiology

authors： Sahukhal GS,Pandey S,Elasri MO

更新日期：2017-11-22 00:00:00

abstract：BACKGROUND:Vibrio anguillarum is an extracellular bacterial pathogen that is a causative agent of vibriosis in finfish and crustaceans with mortality rates ranging from 30% to 100%. Mutations in central metabolism (glycolysis and the TCA cycle) of intracellular pathogens often result in attenuated virulence due to depl...

journal_title：BMC microbiology

authors： Mou X,Spinard EJ,Hillman SL,Nelson DR

更新日期：2017-11-14 00:00:00

abstract：BACKGROUND:Bacterial nucleoid consists of genome DNA, RNA, and hundreds of nucleoid-associated proteins (NAPs). Escherichia coli nucleoid is compacted towards the stationary phase, replacing most log-phase NAPs with the major stationary-phase nucleoid protein, Dps. In contrast, Staphylococcus aureus nucleoid sustains t...

journal_title：BMC microbiology

authors： Ushijima Y,Ohniwa RL,Morikawa K

更新日期：2017-10-02 00:00:00

abstract：BACKGROUND:Total community rDNA was used to determine the diversity of bacteria and archaea from water, wet sediment and microbial mats samples of hot springs in the Eastern lowlands of Eritrea. The temperatures of the springs range from 49.5 °C to 100 °C while pH levels varied from 6.97 to 7.54. Akwar and Maiwooi have...

journal_title：BMC microbiology

authors： Ghilamicael AM,Budambula NLM,Anami SE,Mehari T,Boga HI

更新日期：2017-09-22 00:00:00

abstract：BACKGROUND:The aminoglycoside antibiotic gentamicin was supposed to induce a crosstalk between the Cpx- and the Arc-two-component systems (TCS). Here, we investigated the physical interaction of the respective TCS components and compared the results with their respective gene expression and protein abundance. The findi...

journal_title：BMC microbiology

authors： Ćudić E,Surmann K,Panasia G,Hammer E,Hunke S

更新日期：2017-09-18 00:00:00

abstract：BACKGROUND:Famous Chinese strong-flavored liquor (CSFL) is brewed by microbial consortia in a special fermentation pit (FT). However, the fermentation process was not fully understood owing to the complicate community structure and metabolism. In this study, the process-related dynamics of microbial communities and mai...

journal_title：BMC microbiology

authors： Zhang Y,Zhu X,Li X,Tao Y,Jia J,He X

更新日期：2017-09-15 00:00:00

abstract：BACKGROUND:Non-structural protein 1 (NS1) is a multifunctional protein and a crucial regulatory factor in the replication and pathogenesis of avian influenza virus (AIV). Studies have shown that NS1 can interact with a variety of host proteins to modulate the viral life cycle. We previously generated a monoclonal antib...

journal_title：BMC microbiology

authors： Ma Y,Sun J,Gu L,Bao H,Zhao Y,Shi L,Yao W,Tian G,Wang X,Chen H

更新日期：2017-09-11 00:00:00

abstract：BACKGROUND:Probiotics are increasingly applied to prevent and treat a range of infectious, immune related and gastrointestinal diseases. Despite this, the mechanisms behind the putative effects of probiotics are poorly understood. One of the suggested modes of probiotic action is modulation of the endogenous gut microb...

journal_title：BMC microbiology

authors： Laursen MF,Laursen RP,Larnkjær A,Michaelsen KF,Bahl MI,Licht TR

更新日期：2017-08-17 00:00:00

abstract：BACKGROUND:Many plants have been used in traditional medicine for their antibacterial, antifungal, antiprotozoal, antiviral, antidiarrhoeal, analgesic, antimalarial, antioxidant, anti-inflammatory and anticancer activities. In order to find novel antimicrobial and antiviral agents, the aim of the present study was the ...

journal_title：BMC microbiology

authors： Di Petrillo A,Fais A,Pintus F,Santos-Buelga C,González-Paramás AM,Piras V,Orrù G,Mameli A,Tramontano E,Frau A

更新日期：2017-07-14 00:00:00

abstract：BACKGROUND:Sigma factors are one of the components of RNA polymerase holoenzymes, and an essential factor of transcription initiation in bacteria. Corynebacterium glutamicum possesses seven genes coding for sigma factors, most of which have been studied to some detail; however, the role of SigD in transcriptional regul...

journal_title：BMC microbiology

authors： Taniguchi H,Busche T,Patschkowski T,Niehaus K,Pátek M,Kalinowski J,Wendisch VF

更新日期：2017-07-12 00:00:00

abstract：BACKGROUND:The flame-oxidized stainless steel anode (FO-SSA) is a newly developed electrode that enhances microbial fuel cell (MFC) power generation; however, substrate preference and community structure of the biofilm developed on FO-SSA have not been well characterized. Herein, we investigated the community on FO-SSA...

journal_title：BMC microbiology

authors： Eyiuche NJ,Asakawa S,Yamashita T,Ikeguchi A,Kitamura Y,Yokoyama H

更新日期：2017-06-29 00:00:00

abstract：BACKGROUND:With the growing demand for fossil fuels and the severe energy crisis, lignocellulose is widely regarded as a promising cost-effective renewable resource for ethanol production, and the use of lignocellulose residues as raw material is remarkable. Polar organisms have important value in scientific research a...

journal_title：BMC microbiology

authors： Cong B,Wang N,Liu S,Liu F,Yin X,Shen J

更新日期：2017-05-30 00:00:00

abstract：BACKGROUND:Hepatitis C virus (HCV) core protein and nonstructural protein 4B (NS4B) are potentially oncogenic. Aberrant activation of the Wnt/β-catenin signaling pathway is closely associated with hepatocarcinogenesis. We investigated the effects of HCV type 1b core protein and NS4B on Wnt/β-catenin signaling in variou...

journal_title：BMC microbiology

authors： Jiang XH,Xie YT,Cai YP,Ren J,Ma T

更新日期：2017-05-25 00:00:00

abstract：BACKGROUND:The emergence of carbapenemase producing bacteria, especially New Delhi metallo-β-lactamase (NDM-1) and its variants, worldwide, has raised amajor public health concern. NDM-1 hydrolyzes a wide range of β-lactam antibiotics, including carbapenems, which are the last resort of antibiotics for the treatment of...

journal_title：BMC microbiology

authors： Khan AU,Maryam L,Zarrilli R

更新日期：2017-04-27 00:00:00

abstract：BACKGROUND:Accurate identification of Aspergillus species is a very important subject. Mass spectral fingerprinting using matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) is generally employed for the rapid identification of fungal isolates. However, the results are based on s...

journal_title：BMC microbiology

authors： Nakamura S,Sato H,Tanaka R,Kusuya Y,Takahashi H,Yaguchi T

更新日期：2017-04-26 00:00:00

abstract：BACKGROUND:Establishing an optimal proportion of nitrifying microbial populations, including ammonia-oxidizing bacteria (AOB), nitrite-oxidizing bacteria (NOB), complete nitrite oxidizers (comammox) and ammonia-oxidizing archaea (AOA), is important for ensuring the efficiency of nitrification in water treatment systems...

journal_title：BMC microbiology

authors： Scarascia G,Cheng H,Harb M,Hong PY

更新日期：2017-04-04 00:00:00

abstract：BACKGROUND:Candida krusei has been known to exhibit communal interactions such as pellicle formation and crawling out of nutritional broth. We noticed another possible interaction on agar surfaces, where C. krusei yeast cells formed mycelia along agar surfaces toward each other. We report here the results of experiment...

journal_title：BMC microbiology

authors： Fleischmann J,Broeckling CD,Lyons S

更新日期：2017-03-11 00:00:00

abstract：BACKGROUND:Enterococcus is ubiquitous in nature and is a commensal of both the bovine and human gastrointestinal (GI) tract. It is also associated with clinical infections in humans. Subtherapeutic administration of antibiotics to cattle selects for antibiotic resistant enterococci in the bovine GI tract. Antibiotic re...

journal_title：BMC microbiology

authors： Beukers AG,Zaheer R,Goji N,Amoako KK,Chaves AV,Ward MP,McAllister TA

更新日期：2017-03-08 00:00:00